细胞名称：人弥漫性大B细胞淋巴瘤细胞SU-DHL-5
产品规格：T25培养瓶x1；1.5ml冻存管x2
细胞数量：1x10^6：1x10^6
保存温度：37℃；-198℃
运输方式：常温保温运输；干冰运输
安全等级：1
用途限制
仅供科研2类培养体系
培养体系DMEM高糖培养基+10%FBS+1%三抗
培养温度37℃
二氧化碳浓度5%
简介
人弥漫性大B细胞淋巴瘤细胞SU-DHL-5取自17岁女性供体，该细胞源于DSMZ
注释
Part of:Cancer Cell Line Encyclopedia(CCLE)project.
Part of:COSMIC cell lines project.
Part of:MD Anderson Cell Lines Project.
Characteristics:Genetic heterogeneous,consists of 2 subclones(PubMed=27566572).
Doubling time:~40 hours(DSMZ).
Microsatellite instability:Stable(MSS)(Sanger).
Omics:Array-based CGH.
Omics:CNV analysis.
Omics:Deep exome analysis.
Omics:Deep RNAseq analysis.
Omics:DNA methylation analysis.
Omics:miRNA expression profiling.
Omics:Protein expression by reverse-phase protein arrays.
Omics:SNP array analysis.
Omics:Transcriptome analysis.
Omics:Virome analysis using RNAseq.
Derived from sampling site:Lymph node.
基因突变
HLA信息
/
STR信息
Amelogenin X
CSF1PO 11,13
D3S1358 15,16
D5S818 12,15
D7S820 10
D8S1179 13,15
D13S317 12
D16S539 11,13
D18S51 13,15
D21S11 28,30
FGA 22,23
Penta D 11,12
Penta E 5,19
TH01 6,9
TPOX 8
vWA 17
参考文献
PubMed=27566572;DOI=10.18632/oncotarget.11524
Quentmeier H.,Pommerenke C.,Ammerpohl O.,Geffers R.,Hauer V.,MacLeod R.A.F.,Nagel S.,Romani J.,Rosati E.,Rosen A.,Uphoff C.C.,Zaborski M.,Drexler H.G.
Subclones in B-lymphoma cell lines:isogenic models for the study of gene regulation.
Oncotarget 7:63456-63465(2016)
PubMed=28196595;DOI=10.1016/j.ccell.2017.01.005
Li J.,Zhao W.,Akbani R.,Liu W.,Ju Z.,Ling S.,Vellano C.P.,Roebuck P.,Yu Q.,Eterovic A.K.,Byers L.A.,Davies M.A.,Deng W.,Gopal Y.N.V.,Chen G.,von Euw E.M.,Slamon D.J.,Conklin D.,Heymach J.V.,Gazdar A.F.,Minna J.D.,Myers J.N.,Lu Y.,Mills G.B.,Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)
PubMed=30285677;DOI=10.1186/s12885-018-4840-5
Tan K.-T.,Ding L.-W.,Sun Q.-Y.,Lao Z.-T.,Chien W.,Ren X.,Xiao J.-F.,Loh X.-Y.,Xu L.,Lill M.,Mayakonda A.,Lin D.-C.,Yang H.,Koeffler H.P.
Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines.
BMC Cancer 18:940-940(2018)
PubMed=30894373;DOI=10.1158/0008-5472.CAN-18-2747
Dutil J.,Chen Z.,Monteiro A.N.,Teer J.K.,Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res.79:1263-1273(2019)
PubMed=31068700;DOI=10.1038/s41586-019-1186-3
Ghandi M.,Huang F.W.,Jane-Valbuena J.,Kryukov G.V.,Lo C.C.,McDonald E.R.III,Barretina J.,Gelfand E.T.,Bielski C.M.,Li H.,Hu K.,Andreev-Drakhlin A.Y.,Kim J.,Hess J.M.,Haas B.J.,Aguet F.,Weir B.A.,Rothberg M.V.,Paolella B.R.,Lawrence M.S.,Akbani R.,Lu Y.,Tiv H.L.,Gokhale P.C.,de Weck A.,Mansour A.A.,Oh C.,Shih J.,Hadi K.,Rosen Y.,Bistline J.,Venkatesan K.,Reddy A.,Sonkin D.,Liu M.,Lehar J.,Korn J.M.,Porter D.A.,Jones M.D.,Golji J.,Caponigro G.,Taylor J.E.,Dunning C.M.,Creech A.L.,Warren A.C.,McFarland J.M.,Zamanighomi M.,Kauffmann A.,Stransky N.,Imielinski M.,Maruvka Y.E.,Cherniack A.D.,Tsherniak A.,Vazquez F.,Jaffe J.D.,Lane A.A.,Weinstock D.M.,Johannessen C.M.,Morrissey M.P.,Stegmeier F.,Schlegel R.,Hahn W.C.,Getz G.,Mills G.B.,Boehm J.S.,Golub T.R.,Garraway L.A.,Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)
